TPMS Bone Scaffolds: Design and Mold Fabrication for Future Mechanical Testing

To optimize bone scaffold design for tissue regeneration enhancement, computational modeling and fabrication are the focus of this study to implement Triply Periodic Minimal Surface (TPMS) structures. nTOP topology software is utilized to to design gyroid and diamond TPMS structures, as well as lattice structures for bone scaffolds. The designs are fabricated by casting the scaffold material into 3D printed PVA molds. The aim of this study is to evaluate the mechanical properties, such as compressive strength and stiffness, as well as the tortuosity of these structures, which are vital for nutrient transport and cell migration. The experimental characterization will follow the successful fabrication of these scaffolds in order to preoperly compare between TPMS and lattice designs, with the goal being advancing orthopedic therapy.